Automotive Fleet
MenuMENU
SearchSEARCH

50% of Drivers Use Potentially Impairing RX or OTC Meds

The potential effects of medication while behind the wheel can lead to deadly consequences, yet research finds that healthcare professionals fail to warn up to half of drivers.

July 29, 2022
50% of Drivers Use Potentially Impairing RX or OTC Meds

People who receive a warning from a healthcare professional are 18% less likely to get behind the wheel after taking medication.

2 min to read


Approximately 50% of drivers said they used one or more potentially impairing medications in the past 30 days, according to new research from the AAA Foundation for Traffic Safety. Moreover, the proportion of those choosing to drive is higher among those taking multiple medications — a worrisome fact.

Drug use and driving don't mix — even if it’s a prescription medication. A 2020 study of multiple trauma centers found that 56% of drivers involved in serious injury and fatal crashes tested positive for at least one drug, according to the National Highway Traffic Safety Administration (NHTSA).

Ad Loading...

And, a 2020 traffic safety study from AAA Foundation found that most drivers — some 94% — consider driving after drinking alcohol very or extremely dangerous. But, only 87% feel the same about driving after using potentially impairing medications.

Now, the latest study from AAA Foundation explores drivers’ use of prescription and over-the-counter (OTC) medicines and confirms that motorists lack an understanding of their impact on driving, and healthcare professionals are not helping the problem.

For example, healthcare providers failed to warn many respondents who took prescriptions and over-the-counter medications such as antihistamines, cough medicines, antidepressants, prescription pain medicines, muscle relaxants, sleep aids, and amphetamines about their possible dangerous impact on driving. 

In fact, up to half of drivers who were prescribed and took each type of potentially driver impairing (PDI) medication did not report receiving a warning from their medical provider or pharmacist regarding its possible impacts on driving.

Yet the potential effects can be hazardous when mixed with driving. People may experience dizziness, sleepiness, fainting, blurred vision, slowed movement, and attention problems — all of which can lead to deadly consequences if they occur while behind the wheel.

Ad Loading...

On the upside, those survey respondents who did receive a warning from a healthcare professional were 18% less likely to get behind the wheel after medication use — highlighting the potential benefit of healthcare providers’ counseling to reduce medication-impaired driving.

The AAA Foundation study also examined which types of drugs people were taking and most apt to use before hitting the road. Antihistamines and cough medicines — many available without a prescription — were most commonly used. However, the proportion of drivers that reported driving after use was highest for those who reported amphetamine use, such as Adderall and Dexedrine.

More Safety

A person with hands on the steering wheel driving
Safetyby Judie NuskeyMay 15, 2026

The Distractions You Can’t Turn Off: What Drivers Face Outside the Vehicle

Fleet drivers face constant visual, cognitive, and environmental interruptions the moment they hit the road. From roadside chaos to mental fatigue and digital overload, today’s biggest driving risks often come from outside the vehicle itself.

Read More →
Hail covers the windshield and hood of a black vehicle with text overlay about FLASH Weather AI’s new hail prediction model.
Safetyby News/Media ReleaseMay 13, 2026

FLASH Weather AI Launches First Deep-Learning Hail Prediction Model With High-Resolution Forecasting

FLASH Weather AI has launched a first-of-its-kind hail prediction model capable of forecasting hail size and arrival time at 1-kilometer resolution up to 55 minutes ahead, giving fleets and insurers critical time to prepare for severe storms.

Read More →
Coca-Cola fleet executive smiling beside graphic text reading “Rolling Dollar Signs” about the company’s trucking and fleet strategy.
Safetyby Chris BrownMay 12, 2026

How Coca-Cola United Protects Its Fleet from Growing Legal Risk

As litigation risk rises, vehicles are increasingly targeted. This Coca-Cola bottler shares how it’s reducing exposure through driver training, technology, and a proactive risk management approach.

Read More →
Ad Loading...
Two trucking industry workers talk in front of semi-trucks beside text reading, “The issue isn’t lack of safety technology — it’s lack of alignment.”
SafetyMay 12, 2026

How to Speak the Same Language on Fleet Safety

Drivers, supervisors, and data often speak different safety “languages.” Getting on the same page will drive better results.

Read More →
pictures of a lock with the words Cybersecurity 101
Safetyby Jeanny RoaMay 11, 2026

Fleet Cybersecurity 101: What You Need from Your Technology Vendors

From identity management to third-party certifications, the right technology partner should make security easier to manage. Here are the three building blocks that fleet managers need to stay in control as connected systems scale.

Read More →
Chris Brown sits across from safety experft at Lifesaver mobile in an interview about distracted driving and phone use tech.
Safetyby Chris BrownMay 1, 2026

Reducing Risk by Eliminating Phone Use Behind the Wheel

Distracted driving remains one of the most persistent risks in fleet operations. New approaches focus on removing mobile device use entirely while adding real-time safety support.

Read More →
Ad Loading...
Safetyby Jeanny RoaApril 15, 2026

Distracted Driving in the Age of Smart Tech – Part 2

As distraction risks evolve, fleets are turning to smarter, more connected technologies to better understand what’s happening behind the wheel. Part 2 explores how these tools are helping identify risky behaviors and improve visibility across operations.

Read More →
Safetyby Jeanny RoaApril 11, 2026

 Data Rights, Risks, and Responsibilities After a Crash

What fleets capture to improve safety can also expose them in litigation, forcing leaders to rethink how data is managed, stored, and shared.

Read More →
Driver holding a phone while steering, illustrating distracted driving and the importance of mental awareness and attention on the road for fleet safety.
Safetyby Judie NuskeyApril 10, 2026

From Distraction to Detection: Strengthening Awareness in Fleet Drivers

Distracted driving is often measured by what we can see—phones in hand, eyes off the road. But what about the distractions we can’t? A recent incident raises a bigger question about awareness, attention, and why subtle risks so often go unnoticed.

Read More →
Ad Loading...
Safetyby StaffApril 8, 2026

Lytx 2026 Road Safety Report

While serious crashes are declining, a rise in minor incidents and ongoing risk hotspots underscore the need for continued fleet safety investment.

Read More →